发明公开
EP1207889A1 VACCINE TO CONTROL EQUINE PROTOZOAL MYELOENCEPHALITIS IN HORSES
审中-公开
疫苗的马在PFERDEPROTOZOENMYENZEPHALITIS的治疗
- 专利标题： VACCINE TO CONTROL EQUINE PROTOZOAL MYELOENCEPHALITIS IN HORSES
- 专利标题（中）： 疫苗的马在PFERDEPROTOZOENMYENZEPHALITIS的治疗
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申请号： EP00959829.3申请日： 2000-08-31
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公开(公告)号： EP1207889A1公开(公告)日： 2002-05-29
- 发明人: MANSFIELD, Linda, S. , ROSSANO, Mary, G. , MURPHY, Alice, J. , VRABLE, Ruth, A.
- 申请人： MICHIGAN STATE UNIVERSITY
- 申请人地址： 238 Administration Building East Lansing,Michigan 48824 US
- 专利权人： MICHIGAN STATE UNIVERSITY
- 当前专利权人： MICHIGAN STATE UNIVERSITY
- 当前专利权人地址： 238 Administration Building East Lansing,Michigan 48824 US
- 代理机构： Grünecker, Kinkeldey, Stockmair & SchwanhäusserAnwaltssozietät
- 优先权： US152193P 19990902; US513086 20000224
- 国际公布： WO0115708 20010308
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; A61K38/00 ; A61K39/395 ; C07K1/00 ; C07K14/00 ; C07H21/02 ; C12P21/06 ; C12N15/00 ; C12N5/00
摘要：
The present invention provides vaccines and methods for making the vaccines that actively or passively protect an equid or other animal against Sarcocystis neurona. In particular, the present invention provides vaccines that provide active immunity which comprise a polypeptide or DNA vaccine that contains or expresses at least one epitope of an antigen that has an amino acid sequence substantially similar to a unique 16 (+/-4) kDa antigen and/or 30 (+/-4) kDa antigen of Sarcocystis neurona. The present invention further provides a vaccine that provides passive immunity to Sarcocystis neurona comprising polyclonal or monoclonal antibodies against at least one epitope of an antigen substantially similar to a unique 16 (+/-4) kDa antigen and/or 30 (+/-4) kDa antigen of Sarcocystis neurona.
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