发明公开
EP1208112A1 DRUG TARGET ISOGENES: POLYMORPHISMS IN THE 5-HYDROXYTRYPTAMINE RECEPTOR 1A GENE
审中-公开
药物目的等基因：多态性5-羟色胺1A受体基因
- 专利标题： DRUG TARGET ISOGENES: POLYMORPHISMS IN THE 5-HYDROXYTRYPTAMINE RECEPTOR 1A GENE
- 专利标题（中）： 药物目的等基因：多态性5-羟色胺1A受体基因
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申请号： EP00962018.8申请日： 2000-08-01
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公开(公告)号： EP1208112A1公开(公告)日： 2002-05-29
- 发明人: DENTON, R., Rex , KLIEM, Stefanie, E. , NANDABALAN, Krishnan , STEPHENS, Joel, Claiborne
- 申请人： Genaissance Pharmaceuticals, Inc.
- 申请人地址： Five Science Park New Haven, CT 06511 US
- 专利权人： Genaissance Pharmaceuticals, Inc.
- 当前专利权人： Genaissance Pharmaceuticals, Inc.
- 当前专利权人地址： Five Science Park New Haven, CT 06511 US
- 代理机构： Molnia, David
- 优先权： US147711P 19990806
- 国际公布： WO0110884 20010215
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C07K14/00 ; C07K16/00 ; C12N15/00
摘要：
Polynucleotides comprising one or more of 3 novel single nucleotide polymorphisms in the human 5-hydroxytryptamine receptor 1A gene (HTR1A) gene are described. Compositions and methods for detecting one or more of these polymorphisms are also disclosed. In addition, various genotypes and haplotypes for HTR1A gene that exist in the population are described.
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