发明公开
EP1214408A1 RIBOZYME ZUR RESTENOSE-PRÄVENTION 审中-公开
核酶预防再狭窄

RIBOZYME ZUR RESTENOSE-PRÄVENTION
摘要:
The invention relates to a catalytically active RNA molecule that is directed to mRNA molecules that encode the cell cycle relevant proteins cyclin E or E2F1. The catalytically active RNA molecule is a hammerhead ribozyme that induces the inhibition of the cell cycle of vascular smooth muscle cells in order to prevent restenosis.
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