发明公开
EP1222211A1 PCNA ASSOCIATED CELL CYCLE PROTEINS, COMPOSITIONS AND METHODS OF USE
审中-公开
二手PCNA相关的细胞周期蛋白,组成和方法
- 专利标题: PCNA ASSOCIATED CELL CYCLE PROTEINS, COMPOSITIONS AND METHODS OF USE
- 专利标题(中): 二手PCNA相关的细胞周期蛋白,组成和方法
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申请号: EP00966817.9申请日: 2000-09-22
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公开(公告)号: EP1222211A1公开(公告)日: 2002-07-17
- 发明人: LUO, Ying , HUANG, Betty
- 申请人: Rigel Pharmaceuticals, Inc.
- 申请人地址: 240 E. Grand Avenue South San Francisco, CA 94040 US
- 专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人地址: 240 E. Grand Avenue South San Francisco, CA 94040 US
- 代理机构: Kiddle, Simon John
- 优先权: US404408 19990923
- 国际公布: WO0121663 20010329
- 主分类号: C07K16/40
- IPC分类号: C07K16/40 ; C12N9/22 ; G01N33/566
摘要:
The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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