发明公开
- 专利标题： MOLECULES FOR DISEASE DETECTION AND TREATMENT
- 专利标题（中）： 分子，检测和治疗疾病的
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申请号： EP00965340.3申请日： 2000-09-22
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公开(公告)号： EP1222258A2公开(公告)日： 2002-07-17
- 发明人: HODGSON, David, M. , LINCOLN, Stephen, E. , RUSSO, Frank, D. , SPIRO, Peter, A. , BANVILLE, Steven, C. , BRATCHER; Shawn, R. , DUFOUR; Gerard, E. , COHEN, Howard, J. , ROSEN, Bruce, H: , SHAH, Purvi , CHALUP, Michael, S. , HILLMAN, Jennifer, L. , JONES; Anissa, L. , YU, Jimmy, Y. , GREENAWALT, Lila, B. , PANZER, Scott, R. , ROSEBERRY, Ann, M. , WRIGHT; Rachel, J. , CHEN, Wensheng , LIU, Tommy, F. , YAP, Pierre, E. , STOCKDREHER, Theresa, K. , AMSHEY, Stefan , FONG, Willy, T.
- 申请人： Incyte Genomics, Inc.
- 申请人地址： 3160 Porter Drive Palo Alto, CA 94304 US
- 专利权人： Incyte Genomics, Inc.
- 当前专利权人： Incyte Genomics, Inc.
- 当前专利权人地址： 3160 Porter Drive Palo Alto, CA 94304 US
- 代理机构： Wright, Simon Mark
- 优先权： US156565 19990928; US168197 19991130
- 国际公布： WO0123538 20010405
- 主分类号： C12N15/00
- IPC分类号： C12N15/00 ; C12N15/63 ; C07K14/47 ; C07K16/00 ; C12Q1/68 ; G01N33/68
摘要：
The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.
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