发明公开
- 专利标题： MEDICINAL COMPOSITIONS FOR TREATING AND PREVENTING DISEASES BASED ON ABNORMAL BLOOD COAGULATION
- 专利标题（中）： 医药组合物用于治疗和异常的预防混凝为本病
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申请号： EP00987688.9申请日： 2000-12-21
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公开(公告)号： EP1240901A1公开(公告)日： 2002-09-18
- 发明人: NAKATOMI, Yasushi , TOMOKIYO, Kazuhiko , ARAKI, Tatsuya , TESHIMA, Kaori , WATANABE, Tomoko , NAKAGAKI, Tomohiro
- 申请人： Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 申请人地址： 6-1, Okubo 1-chome Kumamoto-shi, Kumamoto 860-8568 JP
- 专利权人： Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人： Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人地址： 6-1, Okubo 1-chome Kumamoto-shi, Kumamoto 860-8568 JP
- 代理机构： VOSSIUS & PARTNER
- 优先权： JP36812299 19991224
- 国际公布： WO01047548 20010705
- 主分类号： A61K38/37
- IPC分类号： A61K38/37 ; A61K38/36 ; A61P7/04
摘要：
The present invention provides a pharmaceutical composition for treatment and prevention of hemorrhage associated with blood coagulation disorders, comprising activated Factor VII (FVIIa) and Factor X (FX) as an active ingredient. The pharmaceutical composition of the present invention contains no components causative side effects, is safe, highly efficacious, and easy to manage hemostasis. The pharmaceutical composition can be used for hemostatic management of patients suffering from hemorrhage associated with blood coagulation disorders, for example, disorders (including deficiency) of blood coagulation factors, especially caused by inhibitors (antibodies) against blood coagulation factors.
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