发明公开
- 专利标题: BUPROPION METABOLITES AND METHODS OF THEIR SYNTHESIS AND USE
- 专利标题(中): 安非他酮代谢物和其合成方法及用途
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申请号: EP00957684.4申请日: 2000-08-23
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公开(公告)号: EP1259243A2公开(公告)日: 2002-11-27
- 发明人: FANG, Qun, K. , SENANAYAKE, Chrisantha, H. , GROVER, Paul
- 申请人: SEPRACOR, INC.
- 申请人地址: 111 Locke Drive Marlborough, MA 01752 US
- 专利权人: SEPRACOR, INC.
- 当前专利权人: SEPRACOR, INC.
- 当前专利权人地址: 111 Locke Drive Marlborough, MA 01752 US
- 代理机构: Killin, Stephen James
- 优先权: US510241 20000222; US640725 20000818
- 国际公布: WO01062257 20010830
- 主分类号: A61K31/5375
- IPC分类号: A61K31/5375 ; A61K31/137 ; A61P25/24 ; A61P25/34 ; A61P25/20
摘要:
Methods and compositions are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, but are not limited to, sexual dysfunction, affective disorders, cerebral function disorders, cigarette smoking, and incontinence. Methods of making optically pure bupropion metabolites are also disclosed.
公开/授权文献
- EP1259243B2 BUPROPION METABOLITES AND METHODS OF THEIR SYNTHESIS AND USE 公开/授权日:2010-07-21
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