发明公开
EP1265476A2 MQM MAPPING USING HAPLOTYPED PUTATIVE QTL-ALLELES: A SIMPLE APPROACH FOR MAPPING QTL'S IN PLANT BREEDING POPULATIONS
审中-公开
与HAPLOTYPISIERTEN假定的QTL等位基因MQM映射：一种简单的QTL定位年代在PFLANZENZUCHT PROGRAMS
- 专利标题： MQM MAPPING USING HAPLOTYPED PUTATIVE QTL-ALLELES: A SIMPLE APPROACH FOR MAPPING QTL'S IN PLANT BREEDING POPULATIONS
- 专利标题（中）： 与HAPLOTYPISIERTEN假定的QTL等位基因MQM映射：一种简单的QTL定位年代在PFLANZENZUCHT PROGRAMS
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申请号： EP00989407.2申请日： 2000-12-21
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公开(公告)号： EP1265476A2公开(公告)日： 2002-12-18
- 发明人: JANSEN, Ritsert, C. , BEAVIS, William, D.
- 申请人： PIONEER HI-BRED INTERNATIONAL, INC.
- 申请人地址： 800 Capital Square,400 Locust Street Des Moines, Iowa 50309 US
- 专利权人： PIONEER HI-BRED INTERNATIONAL, INC.
- 当前专利权人： PIONEER HI-BRED INTERNATIONAL, INC.
- 当前专利权人地址： 800 Capital Square,400 Locust Street Des Moines, Iowa 50309 US
- 代理机构： Irvine, Jonquil Claire
- 优先权： US173985P 19991230; US175117P 20000106; US180330P 20000204
- 国际公布： WO01049104 20010712
- 主分类号： A01H1/04
- IPC分类号： A01H1/04 ; A01H5/00 ; C12Q1/68
摘要：
Methods for mapping a phenotypic trait to a corresponding chromosomal location are provided. Statistical methods which correlate pedigrees with multiple genetic markers, the haplotype, to determine identical-by-descent (IBD) data are employed to map phenotypic traits. The statistical models provided are a HAPLO-IM+ model, a HAPLO-MQM model, and a HAPLO-MQM+ model. These statistical methods are applied to map traits determined alternatively by single genes or by quantitative trait loci. Methods of marker assisted selection (MAS) using a variety of genetic markers are provided. Plants selected by MAS using the methods are provided. Additionally, methods for cloning nucleic acids corresponding to phenotypic traits that are in linkage disequilibrium with genetic markers are provided, and for transducing them into plant cells are provided. Transgenic plants transduced with the cloned nucleic acids corresponding to phenotypic traits, e.g. QTL, are provided.
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