发明公开
EP1291020A3 Use of cytokines and mitogens to inhibit pathological immune responses
审中-公开
利用细胞因子和有丝分裂原的抑制病理性的免疫反应
- 专利标题: Use of cytokines and mitogens to inhibit pathological immune responses
- 专利标题(中): 利用细胞因子和有丝分裂原的抑制病理性的免疫反应
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申请号: EP02024061.0申请日: 1998-11-05
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公开(公告)号: EP1291020A3公开(公告)日: 2004-05-26
- 发明人: Horwitz, David A.
- 申请人: THE UNIVERSITY OF SOUTHERN CALIFORNIA
- 申请人地址: University Park Los Angeles, California 90089 US
- 专利权人: THE UNIVERSITY OF SOUTHERN CALIFORNIA
- 当前专利权人: THE UNIVERSITY OF SOUTHERN CALIFORNIA
- 当前专利权人地址: University Park Los Angeles, California 90089 US
- 代理机构: Kiddle, Simon John
- 优先权: US64507P 19971105
- 主分类号: A61K35/14
- IPC分类号: A61K35/14 ; A61P37/02
摘要:
Method for ex-vivo inhibition of the production of immunoglobulins in a sample of peripheral blood mononuclear cells (PBMC) by addition of an inhibitory composition (e.g. containing IL-2 or TGF-beta as inhibitor agent) to the cells. Method of treating autoimmune diseases, e.g. systematic lupus erythematosus (SLE), by reintroducing the treated cells to a patient.
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