发明公开
EP1297176A1 MICROORGANISMES AYANT UNE ACTION MODULATRICE DE LA GLYCOSYLATION DE SURFACE DES CELLULES INTESTINALES
有权
微生物类肠细胞的演技OBERFLÄCHENGLYKOLYSIERUNG
- 专利标题： MICROORGANISMES AYANT UNE ACTION MODULATRICE DE LA GLYCOSYLATION DE SURFACE DES CELLULES INTESTINALES
- 专利标题（英）： Micro-organisms with glycosylation modulating action of intestinal cell surface
- 专利标题（中）： 微生物类肠细胞的演技OBERFLÄCHENGLYKOLYSIERUNG
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申请号： EP01951775.4申请日： 2001-07-04
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公开(公告)号： EP1297176A1公开(公告)日： 2003-04-02
- 发明人: ANTOINE, Jean-Michel , FREITAS, Miguel , CAYUELA, Chantal , TRUGNAN, Germain
- 申请人： Compagnie Gervais Danone
- 申请人地址： 126 rue Jules Guesde 92300 Levallois Perret FR
- 专利权人： Compagnie Gervais Danone
- 当前专利权人： Compagnie Gervais Danone
- 当前专利权人地址： 126 rue Jules Guesde 92300 Levallois Perret FR
- 代理机构： Vercaemer, Laurence
- 优先权： FR0008672 20000704
- 国际公布： WO02002800 20020110
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; C12R1/225
摘要：
The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for selecting micro-organism strains, in particular of lactic acid bacteria, which consists in measuring the average fluorescence intensity variation of HT29-MTX cells incubated in the presence of a lectin coupled with a fluorochrome after being in contact with the supernatant of the strain concerned. Said lactic acid bacteria strains can be used, optionally in the form of their active fraction, for preparing food compositions or medicines or food supplements, modulating glycosylation of glycoproteins of intestinal epithelial cells.
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