发明公开
EP1315718A1 BICYCLISCHE HETEROCYCLEN, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL, DEREN VERWENDUNG UND VERFAHREN ZU IHRER HERSTELLUNG
有权
BICYCLISCHE HETEROCYCLEN，DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL，DEREN VERWENDUNG UND VERFAHREN ZU IHRER HERSTELLUNG
- 专利标题： BICYCLISCHE HETEROCYCLEN, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL, DEREN VERWENDUNG UND VERFAHREN ZU IHRER HERSTELLUNG
- 专利标题（英）： Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof
- 专利标题（中）： BICYCLISCHE HETEROCYCLEN，DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL，DEREN VERWENDUNG UND VERFAHREN ZU IHRER HERSTELLUNG
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申请号： EP01976107.1申请日： 2001-08-18
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公开(公告)号： EP1315718A1公开(公告)日： 2003-06-04
- 发明人: HIMMELSBACH, Frank , LANGKOPF, Elke , JUNG, Birgit , BLECH, Stefan , SOLCA, Flavio
- 申请人： Boehringer Ingelheim Pharma GmbH & Co.KG
- 申请人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim Pharma GmbH & Co.KG
- 当前专利权人： Boehringer Ingelheim Pharma GmbH & Co.KG
- 当前专利权人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 优先权： DE10042059 20000826
- 国际公布： WO02018372 20020307
- 主分类号： C07D405/12
- IPC分类号： C07D405/12 ; A61K31/517
摘要：
The invention relates to bicyclic heterocycles of general formula (I), in which Ra to Rd and X are defined as referred to in Claims Nos. 1 to 7, to their tautomers, their stereoisomers, and to their salts, particularly their physiologically compatible salts with inorganic or organic acids or bases, which have valuable pharmacological properties, in particular, an inhibitive effect on the signal transduction imparted by tyrosine kinases. The invention also relates to the use of said bicyclic heterocycles for treating diseases, especially tumor diseases, disorders of the lung and of the respiratory tract, and to the production thereof.
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