发明公开
EP1316610A1 Preparation comprising an enzyme for asymmetrical hydrolysis of N-substituted C3-C4 cyclic imino-2-carboxylic acid ester and method of using the same
有权
它包含N-取代的C3-C4环亚胺-2-羧酸酯和不对称水解的酶的化合物,它们的使用
- 专利标题: Preparation comprising an enzyme for asymmetrical hydrolysis of N-substituted C3-C4 cyclic imino-2-carboxylic acid ester and method of using the same
- 专利标题(中): 它包含N-取代的C3-C4环亚胺-2-羧酸酯和不对称水解的酶的化合物,它们的使用
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申请号: EP02256033.8申请日: 2002-08-30
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公开(公告)号: EP1316610A1公开(公告)日: 2003-06-04
- 发明人: Kawabe, Tomoyasu , Kamitamari, Masashi
- 申请人: Sumitomo Chemical Company, Limited
- 申请人地址: 5-33, Kitahama 4-chome Chuo-ku Osaka 541-8550 JP
- 专利权人: Sumitomo Chemical Company, Limited
- 当前专利权人: Sumitomo Chemical Company, Limited
- 当前专利权人地址: 5-33, Kitahama 4-chome Chuo-ku Osaka 541-8550 JP
- 代理机构: Cresswell, Thomas Anthony
- 优先权: JP2001265495 20010903
- 主分类号: C12N15/55
- IPC分类号: C12N15/55 ; C12N11/08 ; C12N9/18 ; C07D205/08
摘要:
There is disclosed an enzyme preparation comprising: (i) a styrene-divinylbenzene copolymer having fine pores with an average radius of 200 - 500Å, and (ii) an enzyme capable of asymmetrically hydrolyzing N-substituted C3-C4 cyclic imino-2-carboxylic acid ester to preferentially produce an (S)-N-substituted C3-C4 cyclic imino-2-carboxylic acid, wherein said enzyme comprises an amino acid sequence as set forth in SEQ ID NO: 1 or the like.
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