发明公开
- 专利标题: METHOD FOR IDENTIFYING COMPOUNDS WITH ANTI-HERPES ACTIVITY
- 专利标题(中): 方法化合物与抗疱疹有效性鉴定
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申请号: EP00945756.5申请日: 2000-06-15
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公开(公告)号: EP1319185A1公开(公告)日: 2003-06-18
- 发明人: KLEYMANN, Gerald , BETZ, Ulrich , FISCHER, Rüdiger , HENDRIX, Martin , HEWLETT, Guy , PEVZNER, Veniamin
- 申请人: Bayer Aktiengesellschaft , Kleymann, Gerald
- 申请人地址: 51368 Leverkusen DE
- 专利权人: Bayer Aktiengesellschaft,Kleymann, Gerald
- 当前专利权人: Bayer Aktiengesellschaft,Kleymann, Gerald
- 当前专利权人地址: 51368 Leverkusen DE
- 代理机构: Linkenheil, Dieter
- 国际公布: WO01096874 20011220
- 主分类号: G01N33/569
- IPC分类号: G01N33/569 ; G01N33/50
摘要:
The invention relates to a method for identifying compounds with antiviral activity, characterized in that those compounds are selected in the presence of which resistant viral mutants can be selected, wherein at least one selected viral mutant carries at least one mutation in the primase gene and another selected viral mutant carries at least one mutation in the helicase gene or a selected viral mutant carries at least one mutation in the helicase and at least one mutation in the primase gene.
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