发明授权
EP1326968B1 NON-DISRUPTIVE THREE-DIMENSIONAL CULTURE AND HARVEST SYSTEM FOR ANCHORAGE-DEPENDENT CELLS
有权
非侵入式，立体化系统用于培养并收获贴壁依赖性细胞
- 专利标题： NON-DISRUPTIVE THREE-DIMENSIONAL CULTURE AND HARVEST SYSTEM FOR ANCHORAGE-DEPENDENT CELLS
- 专利标题（中）： 非侵入式，立体化系统用于培养并收获贴壁依赖性细胞
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申请号： EP01981506.7申请日： 2001-10-12
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公开(公告)号： EP1326968B1公开(公告)日： 2007-04-18
- 发明人: YU, Harry , LEONG, Kam, W. , CHIA, Ser-Mien
- 申请人： Agency for Science, Technology and Research , The National University of Singapore
- 申请人地址： 20 Biopolis Way, No. 07-01 Centros Singapore 138668 SG
- 专利权人： Agency for Science, Technology and Research,The National University of Singapore
- 当前专利权人： Agency for Science, Technology and Research,The National University of Singapore
- 当前专利权人地址： 20 Biopolis Way, No. 07-01 Centros Singapore 138668 SG
- 代理机构： Viering, Jentschura & Partner
- 优先权： US239259P 20001012
- 国际公布： WO2002031135 20020418
- 主分类号： C12N11/04
- IPC分类号： C12N11/04 ; C12N11/06 ; C12N11/16
摘要：
A multi-layered microcapsule has an inner extracellular matrix and an outer shell. The inner extracellular matrix includes a first inner layer of biopolymer and a second intermediate layer of polymer that provides partial immune-protection and holds the first layer in place. The outer shell can form an exoskeleton to provide mechanical stability. Each of the individual layers can be varied to optimize mechanical stability, cell function, and immuno-protection.
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