发明授权
- 专利标题: ORALLY ACTIVE SALTS WITH TYROSINE KINASE ACTIVITY
- 专利标题(中): 口服活性的盐具有酪氨酸激酶活性
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申请号: EP01987742.2申请日: 2001-10-17
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公开(公告)号: EP1328519B1公开(公告)日: 2005-09-07
- 发明人: FRALEY, Mark, E. , KARKI, Shyam, B. , KIM, Yuntae
- 申请人: Merck & Co., Inc.
- 申请人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构: Horgan, James Michael Frederic
- 优先权: US241043P 20001017
- 国际公布: WO2002032861 20020425
- 主分类号: C07D241/04
- IPC分类号: C07D241/04 ; C07D243/06 ; C07D401/04 ; A61K31/4704 ; A61K31/496 ; A61K31/551
摘要:
The present invention relates to orally active salts of compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.
公开/授权文献
- EP1328519A2 ORALLY ACTIVE SALTS WITH TYROSINE KINASE ACTIVITY 公开/授权日:2003-07-23
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