发明公开
EP1336608A1 DIBENZOSBERANYL PIPERAZINE DERIVATIVES AND DRUG-RESISTANCE OVERCOMING AGENTS CONTAINING THE DERIVATIVES
审中-公开
DIBENZOSUBERANYLPIPERAZINDERIVATE与这些衍生剂含药物来克服阻力
- 专利标题： DIBENZOSBERANYL PIPERAZINE DERIVATIVES AND DRUG-RESISTANCE OVERCOMING AGENTS CONTAINING THE DERIVATIVES
- 专利标题（中）： DIBENZOSUBERANYLPIPERAZINDERIVATE与这些衍生剂含药物来克服阻力
-
申请号： EP01982865.6申请日： 2001-11-20
-
公开(公告)号： EP1336608A1公开(公告)日： 2003-08-20
- 发明人: TAKEUCHI, Tsutomu , TAKAYANAGI, Hiroaki , KOBAYASHI, Seiki , OSA, Yumiko , SUZUKI, Yumiko , SATO, Yoko , SAKAGUCHI, M, POLA CHEM IND,INC YOKOHAMA KENKYUSHO , MIYATA, Y, POLA CHEM. IND.,INC. YOKOHAMA KENKYUSHO
- 申请人： POLA CHEMICAL INDUSTRIES, INC. , Takeuchi, Tsutomu , Takayanagi, Hiroaki
- 申请人地址： 6-48, Yayoi-cho Shizuoka-shi, Shizuoka 420-0914 JP
- 专利权人： POLA CHEMICAL INDUSTRIES, INC.,Takeuchi, Tsutomu,Takayanagi, Hiroaki
- 当前专利权人： POLA CHEMICAL INDUSTRIES, INC.,Takeuchi, Tsutomu,Takayanagi, Hiroaki
- 当前专利权人地址： 6-48, Yayoi-cho Shizuoka-shi, Shizuoka 420-0914 JP
- 代理机构： Hartz, Nikolai F., Dr.
- 优先权： JP2000355393 20001122
- 国际公布： WO02042284 20020530
- 主分类号： C07D295/088
- IPC分类号： C07D295/088 ; C07D295/084 ; A61K31/495 ; A61P43/00 ; A61P33/06
摘要：
Dibenzosuberanyl piperazine derivatives represented by the following formula (I):
wherein R represents an aliphatic hydrocarbon group, which may contain one or more heteroatom-containing substituent groups and may preferably contain 2 to 30 carbon atoms, and physiologically acceptable salts thereof; and medicinal compositions containing these dibenzosuberanyl piperazine derivatives and/or physiologically acceptable salts thereof.
These compounds show effectiveness in allowing resistance-acquired causes of diseases to restore sensitivity to drug, that is, a resistance overcoming effect.
wherein R represents an aliphatic hydrocarbon group, which may contain one or more heteroatom-containing substituent groups and may preferably contain 2 to 30 carbon atoms, and physiologically acceptable salts thereof; and medicinal compositions containing these dibenzosuberanyl piperazine derivatives and/or physiologically acceptable salts thereof.
These compounds show effectiveness in allowing resistance-acquired causes of diseases to restore sensitivity to drug, that is, a resistance overcoming effect.
信息查询
