发明公开
EP1345909A1 PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS
审中-公开
苯基乙酰氨基吡唑衍生物及其抗肿瘤化合物
- 专利标题： PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS
- 专利标题（中）： 苯基乙酰氨基吡唑衍生物及其抗肿瘤化合物
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申请号： EP01983600.6申请日： 2001-11-22
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公开(公告)号： EP1345909A1公开(公告)日： 2003-09-24
- 发明人: PEVARELLO, Paolo , ORSINI, Paolo , TRAQUANDI, Gabriella , BRASCA, Maria, Gabriella , AMICI, Raffaella , VILLA, Manuela , PIUTTI, Claudia , VARASI, Mario , LONGO, Antonio
- 申请人： Pharmacia Italia S.p.A. , Pevarello, Paolo
- 申请人地址： Via Robert Koch 1.2 20152 Milano IT
- 专利权人： Pharmacia Italia S.p.A.,Pevarello, Paolo
- 当前专利权人： Pharmacia Italia S.p.A.,Pevarello, Paolo
- 当前专利权人地址： Via Robert Koch 1.2 20152 Milano IT
- 代理机构： Longoni, Alessandra
- 优先权： US252911P 20001127; US907943 20010719
- 国际公布： WO02048114 20020620
- 主分类号： C07D231/40
- IPC分类号： C07D231/40 ; C07D413/12 ; C07D403/12 ; C07D401/12 ; A61K31/415 ; A61P35/00
摘要：
Phenylacetamido-pyrazoles of Formula (I) and, more particularly, N-(5-cycloalkyl-1H-pyrazol-3-yl) phenylacetamido derivatives, optionally further substituted as reported in the description; or pharmaceutically acceptable salts thereof; are useful in the treatment of cell proliferative disorders, e.g.cancer, associated with an altered cell cycle dependent kinase activity. Formula (I).
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