发明公开
EP1346221A1 A METHOD OF ASSAYING FOR AGONISTS OR ANTAGONIST OF DYNORPHIN A BINDING TO THE MAS RECEPTOR
有权
试验程序激动剂或强啡肽A的TIE的拮抗剂到MAS受体
- 专利标题： A METHOD OF ASSAYING FOR AGONISTS OR ANTAGONIST OF DYNORPHIN A BINDING TO THE MAS RECEPTOR
- 专利标题（中）： 试验程序激动剂或强啡肽A的TIE的拮抗剂到MAS受体
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申请号： EP01272423.3申请日： 2001-12-19
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公开(公告)号： EP1346221A1公开(公告)日： 2003-09-24
- 发明人: AHMAD, SultanAstraZeneca R & D Montréal , GRAZZINI, EricAstraZeneca R & D Montréal , LEMBO, PaolaAstraZeneca R & D Montréal
- 申请人： AstraZeneca AB
- 申请人地址： 151 85 Södertälje SE
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： 151 85 Södertälje SE
- 优先权： US257977P 20001222
- 国际公布： WO02052267 20020704
- 主分类号： G01N33/566
- IPC分类号： G01N33/566 ; C07K14/665 ; C07K14/72
摘要：
The present invention is directed to assays that can be used to screen for compounds that act as agonists or antagonists or inverse agonists of Dynorphin A and its analogues. The assays are based upon the binding of Dynorphin A and its analogues to the rat and human MAS receptors.
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