发明公开
EP1356072A2 COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND SUBSEQUENT MODIFICATION OF URIDINE-5'-DIPHOSPHOSULFOQUINOVOSE (UDP-SQ)
有权
ZUSAMMENSETZUNGNEN和合成及进一步尿苷5'-DIPHOSPHOSULFOQUINOVOSE的改性方法（UDP-SQ）
- 专利标题： COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND SUBSEQUENT MODIFICATION OF URIDINE-5'-DIPHOSPHOSULFOQUINOVOSE (UDP-SQ)
- 专利标题（中）： ZUSAMMENSETZUNGNEN和合成及进一步尿苷5'-DIPHOSPHOSULFOQUINOVOSE的改性方法（UDP-SQ）
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申请号： EP01989258.7申请日： 2001-11-07
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公开(公告)号： EP1356072A2公开(公告)日： 2003-10-29
- 发明人: BENNING, Christoph , SANDA, Sherrie, Lea , YU, Bin,Michigan State University
- 申请人： MICHIGAN STATE UNIVERSITY
- 申请人地址： 238 Administration Building East Lansing,MI 48824-1046 US
- 专利权人： MICHIGAN STATE UNIVERSITY
- 当前专利权人： MICHIGAN STATE UNIVERSITY
- 当前专利权人地址： 238 Administration Building East Lansing,MI 48824-1046 US
- 代理机构： Glawe, Delfs, Moll & Partner
- 优先权： US709020 20001108
- 国际公布： WO02048706 20020620
- 主分类号： C12P19/30
- IPC分类号： C12P19/30 ; C12P19/02 ; C12P11/00
摘要：
The present invention is directed to composition and methods related to the synthesis and modification of uridine-5'-diphospho-sulfoquinovose (UDP-SQ).In particular, the methods of the present invention comprise the utilization of recombinant enzymes from Arabidopsis thaliana, UDP-glucose, and a sulfur donor to synthesize UDP-SQ, and the subsequent modification of UDP-SQ to form compounds inlcuding, but not limited to, 6-sulfo-a-D-quinovosyl diaclyglycerol (SQDG) and alkyl sulfoquinovoside. The compositions and methods of the invention provide a more simple, rapid means of synthesizing UDP-SQ, and the subsequent modification of UDP-SQ to compounds including, but not limited to, SQDG.
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