发明公开
- 专利标题: VIRAL REPORTER PARTICLES
- 专利标题(中): 病毒颗粒记者
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申请号: EP02748361.9申请日: 2002-02-26
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公开(公告)号: EP1368058A2公开(公告)日: 2003-12-10
- 发明人: HAZUDA, Daria, J. , LINEBERGER, Janet, E. , MILLER, Michael, D. , SIMON, Adam, J.
- 申请人: Merck & Co., Inc.
- 申请人地址: 126 East Lincoln Avenue Rahway,New Jersey 07065-0907 US
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: 126 East Lincoln Avenue Rahway,New Jersey 07065-0907 US
- 代理机构: Horgan, James Michael Frederic
- 优先权: US272732P 20010302
- 国际公布: WO02070651 20020912
- 主分类号: A61K39/00
- IPC分类号: A61K39/00
摘要:
The present invention features a chimeric protein containing a β-lactamase region and either a Vpr region or a Vpx region. The chimeric protein can be packaged into a viral reporter particle, introduced into a cell recognized by the viral particle and provide intracellular β-lactamase activity.
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