The present invention relates to a multi-cell tube capable of simultaneously opening and closing a tube having a plurality of separate cells or chambers and a method for efficiently manufacturing the multi-cell tube. A primary object of the present invention is to manufacture a multi-cell tube having two or more cells, which are repeatedly formed in longitudinal and circumferential directions of the tube, in such a manner that fluid can be separately or simultaneously let into and/or out of the respective cells and the respective cells can be individually kept airtight. The multi-cell tube of the present invention for achieving the object comprises a cell unit 10 including a plurality of cells 11 which are arranged in one direction of the tube and have corresponding inlets 12 formed in a direction intersecting with the direction in which the cells are arranged; a supply tube unit 20 which has an opening/closing valve 21 at any one side end thereof and communicates with the inlets 12 of all the cells 11 in a state where the supply tube unit is close to the cells; and an operating tube unit 30, made of inflatable material (e,g. rubber, plastics or the like), which is installed within the supply tube unit 20, is close to the inlets 12 and the cells 11, and has an opening/closing valve 31 at any one side end thereof.