发明公开
- 专利标题: BIARYL COMPOUNDS AS SERINE PROTEASE INHIBITORS
- 专利标题(中): 联芳基ALS丝氨酸蛋白酶抑制剂
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申请号: EP01981772.5申请日: 2001-10-22
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公开(公告)号: EP1383731A1公开(公告)日: 2004-01-28
- 发明人: BABU, Yarlagadda, S. , ROWLAND, Scott, R. , CHAND, Pooran , KOTIAN, Pravin, L. , EL-KATTAN, Yahya , NIWAS, Shri
- 申请人: Biocryst Pharmaceuticals, Inc.
- 申请人地址: 2910 Parkway Lake Drive Birmingham, Alabama 35244 US
- 专利权人: Biocryst Pharmaceuticals, Inc.
- 当前专利权人: Biocryst Pharmaceuticals, Inc.
- 当前专利权人地址: 2910 Parkway Lake Drive Birmingham, Alabama 35244 US
- 代理机构: Zanoli, Enrico
- 优先权: US281735P 20010406
- 国际公布: WO2002034711 20020502
- 主分类号: C07C229/38
- IPC分类号: C07C229/38 ; C07C317/22 ; C07C63/04 ; C07C257/00 ; C07D333/22 ; C07D307/02 ; C07D277/30 ; C07D207/30 ; C07D207/08 ; C07D211/70 ; C07D311/78 ; C07D239/02 ; C07D265/30 ; C07D277/62
摘要:
Compounds of formula (I) are useful as inhibitors of trypsin like serine protease enzymes such as thrombin, factor VIIa, factor Xa, TF/FVIIa, and trypsin. These compounds could be useful to treat and/or prevent clotting disorders, and as anticoagulating agents.
公开/授权文献
- EP1383731B1 BIARYL COMPOUNDS AS SERINE PROTEASE INHIBITORS 公开/授权日:2009-08-05
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