发明公开
EP1384488A2 Method and kit for imaging organs and tissues, using labelled antibodies
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一种用于器官和组织的成像方法和试剂盒,其中标记被使用的抗体
- 专利标题: Method and kit for imaging organs and tissues, using labelled antibodies
- 专利标题(中): 一种用于器官和组织的成像方法和试剂盒,其中标记被使用的抗体
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申请号: EP03076875.8申请日: 1993-04-02
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公开(公告)号: EP1384488A2公开(公告)日: 2004-01-28
- 发明人: The designation of the inventor has not yet been filed
- 申请人: Immunomedics, Inc.
- 申请人地址: 300 American Road Morris Plains, New Jersey 07950 US
- 专利权人: Immunomedics, Inc.
- 当前专利权人: Immunomedics, Inc.
- 当前专利权人地址: 300 American Road Morris Plains, New Jersey 07950 US
- 代理机构: Mercer, Christopher Paul
- 优先权: US866789 19920407
- 主分类号: A61K51/10
- IPC分类号: A61K51/10 ; A61K49/00 ; A61K49/16
摘要:
The invention provides the use of an antibody or antibody fragment which specifically binds a marker produced by or associated with a cell or tissue in an organ of interest, said antibody or antibody fragment being labelled with a radioisotope or with a magnetic resonance image enhancing agent capable of external detection, in the manufacture of a medicament for use in a method of imaging hypoplastic, anatomically displaced or ectopic cells or tissues in a mammalian subject by scintigraphic or magnetic resonance imaging, wherein the amount of the labelled antibody or antibody fragment is sufficient to permit a scintigraphic image or an enhanced magnetic resonance image of said organ to be obtained. Also provided is a kit for use in such methods.
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