发明公开
EP1397125A2 COMPRESSIBLE GUAIFENESIN COMPOSITIONS AND METHOD FOR PRODUCING THEM 有权
可压缩愈创甘油醚组合物及其生产工艺

  • 专利标题: COMPRESSIBLE GUAIFENESIN COMPOSITIONS AND METHOD FOR PRODUCING THEM
  • 专利标题(中): 可压缩愈创甘油醚组合物及其生产工艺
  • 申请号: EP02741904.3
    申请日: 2002-06-07
  • 公开(公告)号: EP1397125A2
    公开(公告)日: 2004-03-17
  • 发明人: UPADHYAY, Ajay, Hasmukhlal
  • 申请人: Rhodia, Inc.
  • 申请人地址: 259 Prospect Plains Road Cranbury,New Jersey 08512 US
  • 专利权人: Rhodia, Inc.
  • 当前专利权人: Rhodia, Inc.
  • 当前专利权人地址: 259 Prospect Plains Road Cranbury,New Jersey 08512 US
  • 代理机构: Kyle, Diana
  • 优先权: US879320 20010612
  • 国际公布: WO2002100389 20021219
  • 主分类号: A61K31/09
  • IPC分类号: A61K31/09 A61K9/20
COMPRESSIBLE GUAIFENESIN COMPOSITIONS AND METHOD FOR PRODUCING THEM
摘要:
A compressible guaifenesin composition containing guaifenesin and a binder and being in the form of particles and wherein by sieve analysis, based on the total weight of the composition, less than about 30 percent by weight of the particles exhibit a particle size of greater than about 425 micrometers and greater than about 80 percent by weight of the particles exhibit a particle size of greater than about 45 micrometers, provides improved flow properties as well improved robustness and flexibility with regard to the processing conditions used to produce dosage forms from such compositions.
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