A motion guide device comprises a track member (1) having a roller rolling surface (1b) thereon, a movable member (2) to be movable relatively to the track member, plural rollers (3), and a roller retainer (10). The movable member has a roller circulation passage including a loaded roller rolling surface (4d) located to be opposed to the roller rolling surface and being arranged to the track member. The rollers, each made of metal, are disposed in the roller circulation passage with a rotation axis of each roller parallel to each other to thereby circulate in response to a relative motion of the movable member to the track member. The roller retainer retains the rollers rotatably and slidably. The movable member has a contact protrusion (16) formed thereon and made of only resin, not metal. Thus, the contact protrusion comes in contact with an axis-line-direction end surface (3a) of each roller that rolls along the loaded roller rolling surface.