The invention relates to a rear wheel (10) of a bicycle, comprising a rim (30) held by spokes (24, 26) in an off-center fashion, said rim being configured by an unsymmetrical rim body (32). Said rim body (32) has a rim base (34) and radially inwards thereof a hollow chamber (36) delimited by hollow chamber walls (37, 38, 39). The spokes (24, 26) are fastened in the hollow chamber (36) on a hollow chamber wall (38) by means of anchoring elements (42), all anchoring elements lying approximately in one plane of anchoring that lies in the edge zone of the rim base (34). In order to achieve this, a hollow chamber wall (37) adjoining the anchoring elements protrude laterally beyond the rim base (34) in a protuberance. In order to allow a strongly off-set arrangement of the anchoring elements, the lateral hollow chamber is bulged outwards to such an extent that the anchoring elements remain disposed within the hollow chamber (36) and are protected.