发明授权
- 专利标题： INHIBITION OF APOPTOSIS PROCESS AND IMPROVEMENT OF CELL PERFORMANCE
- 专利标题（中）： 细胞凋亡过程的抑制和改善电池性能
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申请号： EP02742400.1申请日： 2002-07-10
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公开(公告)号： EP1414948B1公开(公告)日： 2009-09-16
- 发明人: REFF, Mitchell , BETENBAUGH, Michael, J. , FIGUEROA, Bruno, Jr. , AILOR, Eric , HARDWICK, Marie
- 申请人： Biogen Idec Inc. , JOHNS HOPKINS UNIVERSITY
- 申请人地址： 14 Cambridge Center Cambridge, MA 02142 US
- 专利权人： Biogen Idec Inc.,JOHNS HOPKINS UNIVERSITY
- 当前专利权人： Biogen Idec Inc.,JOHNS HOPKINS UNIVERSITY
- 当前专利权人地址： 14 Cambridge Center Cambridge, MA 02142 US
- 代理机构： Vossius & Partner
- 优先权： US303813P 20010710
- 国际公布： WO2003006607 20030123
- 主分类号： C12N5/10
- IPC分类号： C12N5/10 ; C12N5/06 ; C12N5/08 ; C12P21/00 ; C07H21/00 ; C07K14/00
摘要：
The present invention relates to preventing or delaying programmed cell death by expressing one or more anti-apoptotic polypeptides in a cell such that programmed cell death in the cell is prevented or delayed. The present invention also relates to increasing production of a cell-related product by expressing one or more anti-apoptotic polypeptides in a cell such that production of the cell-related product by the cell is increased. Recombinant cells useful for producing cell-related product or cellular therapy are also provided.
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