The invention relates to the use of 2-alkoxyestrogen sulfamates of general formula (I) for producing a medicament for the treatment of tumorous diseases, which are positively influenced by the inhibition of tubulin polymerisation. In said formula, R?1 and R2¿ independently of one another represent H, methyl, C¿1?-C4 acyl or benzyl, R?3¿ represents C¿1?-C4 alkyl, or a group of formula CnFmHo, where n = 1, 2, 3, 4, 5 or 6, m > 1 and m + o = 2n + 1, R?4 and R5¿ independently represent H, or together represent a methylene group or an additional bond, R6 represents H and R7 represents OH, OC¿1?-C4 alkyl, OC1-C11 acyl or OSO2NR?1R2¿, whereby in the B and C ring of the steroid skeleton the broken lines can additionally represent up to two double bonds. The inventive compounds are characterised by a 2-alkoxy substitution in conjunction with a 17-hydroxy substitution. They exhibit the specific activity of inhibiting tubulin polymerisation and can be used, for example, for treating prostatic carcinoma.