发明授权
EP1426044B1 Use of esters of L-carnitine or alkanoyl L-carnitines as cationic lipids for the intracellular delivery of pharmacologically active compounds
有权
用作阳离子脂质的L-肉碱的酸或烷酰基L-肉碱酸的酯的用于治疗物质的细胞内递送
- 专利标题： Use of esters of L-carnitine or alkanoyl L-carnitines as cationic lipids for the intracellular delivery of pharmacologically active compounds
- 专利标题（中）： 用作阳离子脂质的L-肉碱的酸或烷酰基L-肉碱酸的酯的用于治疗物质的细胞内递送
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申请号： EP03020049.7申请日： 2000-04-11
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公开(公告)号： EP1426044B1公开(公告)日： 2006-02-08
- 发明人: Pisano, Claudio , Tinti, Maria Ornella , Santaniello, Mosè , Critelli, Luciana , Salvatori, Giovanni
- 申请人： SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.
- 申请人地址： Viale Shakespeare, 47 00144 Roma IT
- 专利权人： SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.
- 当前专利权人： SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.
- 当前专利权人地址： Viale Shakespeare, 47 00144 Roma IT
- 代理机构： Spadaro, Marco
- 优先权： ITRM990220 19990413
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61P35/00
摘要：
The use of esters of L-carnitine and alkanoyl L-carnitines as cationic lipids for the intracellular delivery of pharmacologically active compounds is described. The esters according to the invention have general formula (II) wherein the R groups are as defined in the description.
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