发明公开
EP1426449A1 METHOD OF EVALUATING DEGREE OF CANCERATION OF MAMMAL-ORIGIN SPECIMEN
审中-公开
评估哺乳动物源性样本癌症程度的方法
- 专利标题： METHOD OF EVALUATING DEGREE OF CANCERATION OF MAMMAL-ORIGIN SPECIMEN
- 专利标题（中）： 评估哺乳动物源性样本癌症程度的方法
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申请号： EP02755897.2申请日： 2002-08-09
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公开(公告)号： EP1426449A1公开(公告)日： 2004-06-09
- 发明人: USHIJIMA, T. 1817,Nat. Cancer Tsukijilodging House , MIYAMOTO, Kazuaki
- 申请人： Sumitomo Chemical Company, Limited , JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 申请人地址： 5-33, Kitahama 4-chome, Chuo-ku Osaka-shi Osaka 541-8550 JP
- 专利权人： Sumitomo Chemical Company, Limited,JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 当前专利权人： Sumitomo Chemical Company, Limited,JAPAN as represented by PRESIDENT OF NATIONAL CANCER CENTER
- 当前专利权人地址： 5-33, Kitahama 4-chome, Chuo-ku Osaka-shi Osaka 541-8550 JP
- 代理机构： Duckworth, Timothy John
- 优先权： JP2001252804 20010823
- 国际公布： WO2003018840 20030306
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; A61K45/00 ; A61P35/00 ; G01N33/50
摘要：
The present invention relates to a method for assessing a cancerous state of a mammal-derived specimen, which comprises:
(1) a first step of measuring a methylation frequency of Heparan sulfate D-glucosaminyl 3-0-sulfotransferase gene contained in a mammal-derived specimen or an index value having the correlation therewith, and
(2) a second step of determining a cancerous state of the specimen based on a difference obtained by comparing the measured methylation frequency or the index value having the correlation therewith, with a control; and the like.
(1) a first step of measuring a methylation frequency of Heparan sulfate D-glucosaminyl 3-0-sulfotransferase gene contained in a mammal-derived specimen or an index value having the correlation therewith, and
(2) a second step of determining a cancerous state of the specimen based on a difference obtained by comparing the measured methylation frequency or the index value having the correlation therewith, with a control; and the like.
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