发明公开
EP1453538A2 METHOD OF PURIFYING HEPATITIS A VIRUS PARTICLES AND VACCINE PREPARATION
审中-公开
清理方法A型肝炎病毒颗粒和疫苗的
- 专利标题: METHOD OF PURIFYING HEPATITIS A VIRUS PARTICLES AND VACCINE PREPARATION
- 专利标题(中): 清理方法A型肝炎病毒颗粒和疫苗的
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申请号: EP02792955.3申请日: 2002-12-10
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公开(公告)号: EP1453538A2公开(公告)日: 2004-09-08
- 发明人: TAUER, Christa , MEYER, Heidi , MITTERER, Artur , BARRETT, Noel
- 申请人: Baxter Healthcare S.A.
- 申请人地址: Hertistrasse 2 8304 Wallisellen CH
- 专利权人: Baxter Healthcare S.A.
- 当前专利权人: Baxter Healthcare S.A.
- 当前专利权人地址: Hertistrasse 2 8304 Wallisellen CH
- 代理机构: Müller-Boré & PartnerPatentanwälte
- 优先权: US6205 20011210
- 国际公布: WO2003049766 20030619
- 主分类号: A61K39/29
- IPC分类号: A61K39/29 ; C12N7/02
摘要:
The present invention provides methods of purification of Hepatitis A Virus from the supernatant of an infected cell culture and production of a preparation of purified HAV antigen. The present invention is also directed to an HAV vaccine composition comprising a preparation consisting of purified mature HAV particles in an amount sufficient to induce a protective immune response in a mammal.
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