发明公开
EP1453538A2 METHOD OF PURIFYING HEPATITIS A VIRUS PARTICLES AND VACCINE PREPARATION 审中-公开
清理方法A型肝炎病毒颗粒和疫苗的

METHOD OF PURIFYING HEPATITIS A VIRUS PARTICLES AND VACCINE PREPARATION
摘要:
The present invention provides methods of purification of Hepatitis A Virus from the supernatant of an infected cell culture and production of a preparation of purified HAV antigen. The present invention is also directed to an HAV vaccine composition comprising a preparation consisting of purified mature HAV particles in an amount sufficient to induce a protective immune response in a mammal.
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