发明授权
- 专利标题： METHOD AND KIT OF JUDGING THE ONSET OF RHEUMATOID ARTHRITIS
- 专利标题（中）： 方法和试剂盒用于评估类风湿性关节炎爆发
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申请号： EP03700501.4申请日： 2003-01-08
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公开(公告)号： EP1471143B1公开(公告)日： 2008-02-27
- 发明人: SHIOZAWA, Shunichi , KOMAI, Koichiro , NAKATSUKASA, Mikiko
- 申请人： Shiozawa, Shunichi
- 申请人地址： 11-6, Takenodai 2-chome, Nishiku Kobe-shi, Hyogo 651-2274 JP
- 专利权人： Shiozawa, Shunichi
- 当前专利权人： Shiozawa, Shunichi
- 当前专利权人地址： 11-6, Takenodai 2-chome, Nishiku Kobe-shi, Hyogo 651-2274 JP
- 代理机构： Bentz, Jean-Paul
- 优先权： JP2002005326 20020111
- 国际公布： WO2003060126 20030724
- 主分类号： C07K14/515
- IPC分类号： C07K14/515 ; C12Q1/68 ; A61K45/00 ; A61K38/17 ; A61K48/00
摘要：
A gene comprising the amino acid represented by SEQ ID NO:1 and having a glycine insertion mutation as the 269th amino acid in the sequence is identified as an RA disease sensitive gene on human 8th chromosome. Moreover, it is clarified that the mutation in this gene and its protein relates to the onset of RA so as to establish a method of highly accurately judging the onset of RA or the onset risk thereof, etc.
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