An object of the present invention to provide a cartridge syringe and an ophthalmologic syringe set equipped with the cartridge syringe, where the cartridge syringe can be used repeatedly by only exchanging the cartridge containing an ophthalmologic therapeutic agent, and to reduce the amount of waste products and ensure storage space for the ophthalmologic therapeutic agents. The cartridge syringe 1 of the present invention comprises a syringe body 3 having a cartridge housing portion 11, a needle holding member 5 that is disposed in a connectable manner to the tip of the syringe body 3, and a plunger 7 that is slidably disposed on a base-end side of the syringe body 3, the plunger 7 having a pusher 37 at the tip thereof, wherein a one-touch loading mechanism is provided in the syringe body 3 or at a coupling portion between the syringe body 3 and the plunger 7, the one-touch loading mechanism allowing the position of the plunger 7 to be temporarily changed such that the cartridge 9 can be loaded into the syringe body 3.