发明公开
- 专利标题: Cks1 INHIBITORS
- 专利标题(中): CKS1抑制剂
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申请号: EP03711050.9申请日: 2003-02-12
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公开(公告)号: EP1480995A2公开(公告)日: 2004-12-01
- 发明人: WALTER, Annette, O. , REINHARD, Christoph , JEFFERSON, Anne, B. , SHAMOON, Blanche-Marie, F.
- 申请人: CHIRON CORPORATION
- 申请人地址: 4560 Horton Street EmeryvilleCalifornia 94608-2916 US
- 专利权人: CHIRON CORPORATION
- 当前专利权人: CHIRON CORPORATION
- 当前专利权人地址: 4560 Horton Street EmeryvilleCalifornia 94608-2916 US
- 代理机构: UEXKÜLL & STOLBERG
- 优先权: US356906P 20020212
- 国际公布: WO2003068939 20030821
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C07H21/02 ; A61K48/00
摘要:
Inhibitors of human Cks1 and human Skp2, including antisense oligonucleotides, methods, and compositions specific for human Cks1 and human Skp2, are provided. Methods of using the compositions for modulating Cks1 expression and Skp2 expression, and for regulating cell growth, particularly tumor cell growth, are also provided.
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