- 专利标题： VERBESSERTES VERFAHREN ZUR HERSTELLUNG VON VITAMIN B12
- 专利标题（英）： Improved method for the production of vitamin b12
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申请号： EP03745269.5申请日： 2003-03-24
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公开(公告)号： EP1492877A2公开(公告)日： 2005-01-05
- 发明人: WARREN, Martin, J. , DEERY, Evelyne , LEECH, Helen
- 申请人： BASF AKTIENGESELLSCHAFT
- 申请人地址： 67056 Ludwigshafen DE
- 专利权人： BASF AKTIENGESELLSCHAFT
- 当前专利权人： BASF AKTIENGESELLSCHAFT
- 当前专利权人地址： 67056 Ludwigshafen DE
- 代理机构： Fitzner, Uwe, Dr.
- 优先权： DE10214286 20020328; DE10254362 20021121
- 国际公布： WO2003083123 20031009
- 主分类号： C12P19/42
- IPC分类号： C12P19/42
摘要：
The invention relates to an improved method for producing vitamin B12, according to which a culture containing a microorganism in which at least the enzymes uroporphyrinogen-III-methyltransferase and precorrin-2-dehydrogenase that are involved in sirohaem synthesis have an increased activity as opposed to the corresponding endogenous enzyme activities is fermented.
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