发明公开
EP1494677A1 USE OF METHYLENE BLUE AND RELATED COMPOUNDS TO PREVENT OR REVERSE AN EXAGGERATED HEMODYNAMIC REACTION 审中-公开
使用亚甲蓝和防止或逆转夸张的血流动力学反应相关的化合物

USE OF METHYLENE BLUE AND RELATED COMPOUNDS TO PREVENT OR REVERSE AN EXAGGERATED HEMODYNAMIC REACTION
摘要:
The present invention relates to the use of the dye methylene blue (MB) or a related compound to prevent or reverse an exaggerated hemodynamic reaction in animals in need thereof, including humans. More specifically, the present invention concerns the use of MB or a related compound to prevent or reverse hypotension, unstable angina, myocardial infarction or shock caused by the concomitant ingestion of a phosphodiesterase inhibitor, such as sildenafil citrate, and a NO-donor, such as L-arginine, or an organic nitrate, such as nitroglycerin.
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