发明公开
- 专利标题: GENE AMPLIFICATION IN CANCER
- 专利标题(中): 基因扩增用于癌症
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申请号: EP03716689.9申请日: 2003-03-18
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公开(公告)号: EP1497642A2公开(公告)日: 2005-01-19
- 发明人: LI, Jing , POWERS, Scott , YANG, Jianxin
- 申请人: Tularik, Inc.
- 申请人地址: 1120 Veterans Boulevard South San Francisco,California 94080 US
- 专利权人: Tularik, Inc.
- 当前专利权人: Tularik, Inc.
- 当前专利权人地址: 1120 Veterans Boulevard South San Francisco,California 94080 US
- 代理机构: Wakerley, Helen Rachael
- 优先权: US365192P 20020319; US365206P 20020319
- 国际公布: WO2003079982 20031002
- 主分类号: G01N33/00
- IPC分类号: G01N33/00
摘要:
There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the CTSZ and CD24 genes, which are amplified colon cancer and/or ovarian cancer and/or breast cancer genes. The CTSZ and CD24 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vaccine; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.
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