发明授权
EP1501830B1 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES
有权
7-芳基 - 3,9-二氮杂双环[3.3.1]壬-6-烯衍生物及其AS肾素抑制剂用于治疗高血压的治疗，心血管疾病和肾病
- 专利标题： 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES
- 专利标题（中）： 7-芳基 - 3,9-二氮杂双环[3.3.1]壬-6-烯衍生物及其AS肾素抑制剂用于治疗高血压的治疗，心血管疾病和肾病
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申请号： EP03727287.9申请日： 2003-04-08
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公开(公告)号： EP1501830B1公开(公告)日： 2011-10-05
- 发明人: BEZENCON, Olivier , BUR, Daniel , FISCHLI, Walter , REMEN, Lubos , RICHARD-BILDSTEIN, Sylvia , WEBER, Hans-Peter , WELLER, Thomas
- 申请人： Actelion Pharmaceuticals Ltd.
- 申请人地址： Gewerbestrasse 16 4123 Allschwil CH
- 专利权人： Actelion Pharmaceuticals Ltd.
- 当前专利权人： Actelion Pharmaceuticals Ltd.
- 当前专利权人地址： Gewerbestrasse 16 4123 Allschwil CH
- 代理机构： Schager, Frank
- 优先权： PCT/EP02/04705 20020429
- 国际公布： WO2003093267 20031113
- 主分类号： C07D471/08
- IPC分类号： C07D471/08 ; A61K31/4995
摘要：
The invention relates to novel 3,9-diazabicyclo[3.3.1]nonene derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors or renin.
公开/授权文献
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