发明授权
- 专利标题: CALCIUM RECEPTOR MODULATING AGENTS
- 专利标题(中): 钙受体调节剂
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申请号: EP03736701.8申请日: 2003-05-23
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公开(公告)号: EP1509518B1公开(公告)日: 2012-02-08
- 发明人: KELLY, Michael, G. , XU, Shimin , XI, Ning , TOWNSEND, Robert , SEMIN, David, J. , GHIRON, Chiara , COUTLER, Thomas
- 申请人: Amgen, Inc.
- 申请人地址: One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
- 专利权人: Amgen, Inc.
- 当前专利权人: Amgen, Inc.
- 当前专利权人地址: One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
- 代理机构: Grünecker, Kinkeldey, Stockmair & Schwanhäusser
- 优先权: US383270P 20020523; US444945 20030522
- 国际公布: WO2003099814 20031204
- 主分类号: C07D413/04
- IPC分类号: C07D413/04 ; C07D491/04 ; C07D471/04 ; C07D403/04 ; C07D401/04 ; C07D249/18 ; C07D235/08 ; C07D209/86 ; C07D209/80 ; C07D209/12 ; C07D209/10 ; C07D209/08
摘要:
The compounds of the invention are represented by the following general structure (I) or a pharmaceutically acceptable salt thereof, and compositions containing them, wherein the variables are defined herein, and their use to reduce or inhibit PTH secretion, including methods for reducing or inhibiting PTH secretion and methods for treatment or prophylaxis of diseases associated with bone disorders, such as osteoporosis, or associated with excessive secretion of PTH, such as hyperparathyroidism. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
公开/授权文献
- EP1509518A1 CALCIUM RECEPTOR MODULATING AGENTS 公开/授权日:2005-03-02
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