发明公开
EP1524992A2 VACCINE COMPOSITIONS COMPRISING L2 AND/OR L3 IMMUNOTYPE LIPOOLIGOSACCHARIDES FROM LGTB- NEISSERIA MINIGITIDIS
有权
疫苗一起沉降LGTB-脑膜炎奈瑟氏球菌的L2和/或L3免疫型LIPOOLIGOSACCHARIDS CONTAIN
- 专利标题： VACCINE COMPOSITIONS COMPRISING L2 AND/OR L3 IMMUNOTYPE LIPOOLIGOSACCHARIDES FROM LGTB- NEISSERIA MINIGITIDIS
- 专利标题（中）： 疫苗一起沉降LGTB-脑膜炎奈瑟氏球菌的L2和/或L3免疫型LIPOOLIGOSACCHARIDS CONTAIN
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申请号： EP03784152.5申请日： 2003-07-31
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公开(公告)号： EP1524992A2公开(公告)日： 2005-04-27
- 发明人: BIEMANS, Ralph,GlaxoSmithKline Biologicals S.A. , DENOEL, Philippe,GlaxoSmithKline Biologicals S.A. , FERON, ChristianeGlaxoSmithKline Biologicals S.A. , GORAJ, Carine,GlaxoSmithKline Biologicals S.A. , POOLMAN, Jan,GlaxoSmithKline Biologicals S.A. , WEYNANTS, VincentGlaxoSmithKline Biologicals S.A.
- 申请人： GlaxoSmithKline Biologicals S.A.
- 申请人地址： Rue de l'Institut 89 1330 Rixensart BE
- 专利权人： GlaxoSmithKline Biologicals S.A.
- 当前专利权人： GlaxoSmithKline Biologicals S.A.
- 当前专利权人地址： Rue de l'Institut 89 1330 Rixensart BE
- 代理机构： Lubienski, Michael John
- 优先权： GB0218037 20020802; GB0218036 20020802; GB0218035 20020802; GB0218051 20020802; GB0220197 20020830; GB0220199 20020830; GB0225524 20021101; GB0225531 20021101; GB0230164 20021224; GB0230168 20021224; GB0230170 20021224; GB0305028 20030305
- 国际公布： WO2004014417 20040219
- 主分类号： A61K39/095
- IPC分类号： A61K39/095 ; C12N1/21 ; A61P37/04 ; A61K39/102
摘要：
The present invention relates to immunogenic compositions and vaccines for the treatment and prevention of Neisserial disease. Immunogenic compositions of the invention contain combinations of antigens selected from at least two different classes of antigens including adhesins, autotransporter proteins, toxins, iron acquisitions proteins and membrane-associated protein (preferably integral outer membrane protein)s. Such combinations of antigens are able to target the immune response against different aspects of the neisserial life cycle, resulting in a more effective immune response.
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