发明公开
EP1536012A1 HUMAN ANTIHUMAN INTERLEUKIN-6 ANTIBODY AND FRAGMENT OF THE ANTIBODY
审中-公开
MENSCHLICHER ANTI-MENSCH-INTERLEUKIN-6-ANTIKÖRPERSOWIE FRAGMENT DESANTIKÖRPERS
- 专利标题： HUMAN ANTIHUMAN INTERLEUKIN-6 ANTIBODY AND FRAGMENT OF THE ANTIBODY
- 专利标题（中）： MENSCHLICHER ANTI-MENSCH-INTERLEUKIN-6-ANTIKÖRPERSOWIE FRAGMENT DESANTIKÖRPERS
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申请号： EP03791369.6申请日： 2003-08-28
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公开(公告)号： EP1536012A1公开(公告)日： 2005-06-01
- 发明人: SUGIMURA, Kazuhisa , YOSHIZAKI, Kazuyuki , Nakashima, Toshihiro , Sasaki, Takumi
- 申请人： Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 申请人地址： 6-1, Okubo 1-chome Kumamoto-shi, Kumamoto 860-8568 JP
- 专利权人： Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人： Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute
- 当前专利权人地址： 6-1, Okubo 1-chome Kumamoto-shi, Kumamoto 860-8568 JP
- 代理机构： Helbing, Jörg, Dr. Dipl.-Chem.
- 优先权： JP2002253036 20020830
- 国际公布： WO2004020633 20040311
- 主分类号： C12N15/13
- IPC分类号： C12N15/13 ; C07K16/24 ; A61K39/395 ; A61P19/02 ; A61P29/00
摘要：
A substance effective for treating immunopathy where interleukin 6 (IL-6) is involved is provided. A human anti-human IL-6 antibody and a human anti-human IL-6 antibody fragment having a high affinity to human IL-6 were obtained using phage antibody technique. Said antibody and antibody fragment are expected to be useful as a medicament for treating inflammation and immunopathy caused by IL-6.
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