发明授权
EP1543124B1 DNA ENCODING FLAVIN-ADENINE-DINUCLEOTIDE-DEPENDENT-D-ERYTHRONATE-4-PHOSPHATE-DEHYDROGENASE , PDXR , AND MICROBIAL PRODUCTION OF VITAMIN B6
有权
DNA编码黄素腺嘌呤二核苷酸ABHÄNGIGE-D-ERYTHRONAT -4-磷酸脱氢酶，PDXR，和维生素B6的微生物生产
- 专利标题： DNA ENCODING FLAVIN-ADENINE-DINUCLEOTIDE-DEPENDENT-D-ERYTHRONATE-4-PHOSPHATE-DEHYDROGENASE , PDXR , AND MICROBIAL PRODUCTION OF VITAMIN B6
- 专利标题（中）： DNA编码黄素腺嘌呤二核苷酸ABHÄNGIGE-D-ERYTHRONAT -4-磷酸脱氢酶，PDXR，和维生素B6的微生物生产
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申请号： EP03750631.8申请日： 2003-09-25
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公开(公告)号： EP1543124B1公开(公告)日： 2009-09-16
- 发明人: HOSHINO, Tatsuo , ICHIKAWA, Keiko , TAZOE, Masaaki
- 申请人： DSM IP Assets B.V.
- 申请人地址： Het Overloon 1 6411 TE Heerlen NL
- 专利权人： DSM IP Assets B.V.
- 当前专利权人： DSM IP Assets B.V.
- 当前专利权人地址： Het Overloon 1 6411 TE Heerlen NL
- 代理机构： Keller, Günter
- 优先权： EP02021641 20020927
- 国际公布： WO2004029250 20040408
- 主分类号： C12N15/53
- IPC分类号： C12N15/53 ; C12N9/04 ; C12P19/42
摘要：
The present invention relates to a DNA encoding a novel flavin adenine dinucleotide (FAD)-dependent D-erythronate 4-phosphate (EN4P) dehydrogenase originated from Sinorhizobium meliloti, which is involved in vitamin B6 biosynthesis, and a recombinant microorganism transformed with a vector having the DNA. It also relates to a process for production of vitamin B6 by using the recombinant microorganism. 'Vitamin B6' as used in this invention includes pyridoxol (PN), pyridoxal and pyridoxamine. Vitamin B6 is a vitamin indispensable to human beings or other animals, and is used as a raw material of medicines or as feed additives.
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