发明公开
EP1544194A1 4-(SUBSTITUTED ARYL)-5-HYDROXYISOQUINOLINONE DERIVATIVE
审中-公开
4-（SUBSTITUIERTES ARYL）-5-羟基氧杂环戊二烯
- 专利标题： 4-(SUBSTITUTED ARYL)-5-HYDROXYISOQUINOLINONE DERIVATIVE
- 专利标题（中）： 4-（SUBSTITUIERTES ARYL）-5-羟基氧杂环戊二烯
-
申请号： EP03765364.9申请日： 2003-07-23
-
公开(公告)号： EP1544194A1公开(公告)日： 2005-06-22
- 发明人: SHIGA, Futoshi , KANDA, Takahiro , KIMURA, Tetsuya , TAKANO, Yasuo , ISHIYAMA, Junichi , KAWAI, Tomoyuki , ANRAKU, Tsuyoshi , ISHIKAWA, Kumi
- 申请人： KYORIN PHARMACEUTICAL CO., LTD.
- 申请人地址： 5, Kanda Surugadai 2-chome Chiyoda-ku, Tokyo 101-0062 JP
- 专利权人： KYORIN PHARMACEUTICAL CO., LTD.
- 当前专利权人： KYORIN PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： 5, Kanda Surugadai 2-chome Chiyoda-ku, Tokyo 101-0062 JP
- 代理机构： Merkle, Gebhard
- 优先权： JP2002214673 20020724
- 国际公布： WO2004009556 20040129
- 主分类号： C07D217/24
- IPC分类号： C07D217/24 ; C07D401/10 ; C07D401/12 ; A61K31/472 ; A61K31/4725 ; A61K31/496 ; A61K31/5377 ; A61P3/10 ; A61P9/00 ; A61P9/10 ; A61P13/12 ; A61P17/02 ; A61P19/02 ; A61P25/14 ; A61P25/16 ; A61P25/28 ; A61P29/00 ; A61P37/00 ; A61P43/00
摘要：
The invention provides 4-substituted aryl-5-hydroxyisoquinolinone derivatives and their pharmacologically acceptable addition salts with excellent inhibitory effect on poly (ADP-ribose) synthetase.
4-Substituted aryl-5-hydroxyisoquinolinone derivatives, represented by a general formula (1)
and their pharmacologically acceptable addition salts.
4-Substituted aryl-5-hydroxyisoquinolinone derivatives, represented by a general formula (1)
and their pharmacologically acceptable addition salts.
信息查询
