发明公开
EP1551388A2 COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER, COMPOSITIONS THEREOF AND METHODS THEREWITH
审中-公开
用于癌症的治疗中有用链接,THEREOF组合物和程序
- 专利标题: COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER, COMPOSITIONS THEREOF AND METHODS THEREWITH
- 专利标题(中): 用于癌症的治疗中有用链接,THEREOF组合物和程序
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申请号: EP03760389.1申请日: 2003-06-17
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公开(公告)号: EP1551388A2公开(公告)日: 2005-07-13
- 发明人: MCKENNA, Jeffrey , MERCURIO, Frank , PLANTEVIN, Veronique , XIE, Weilin
- 申请人: Signal Pharmaceuticals, Inc.
- 申请人地址: 4550 Towne Centre Court San Diego, CA 92121 US
- 专利权人: Signal Pharmaceuticals, Inc.
- 当前专利权人: Signal Pharmaceuticals, Inc.
- 当前专利权人地址: 4550 Towne Centre Court San Diego, CA 92121 US
- 代理机构: Jones Day
- 优先权: US389461P 20020617; US463009 20030616
- 国际公布: WO2003105774 20031224
- 主分类号: A61K31/35
- IPC分类号: A61K31/35
摘要:
The present invention generally relates to compounds and compositions useful for the modulation of ligase activity. The invention further relates to Compounds of the Invention, compositions thereof, and methods for treating or preventing cancer, a neoplastic disorder, acute or chronic renal failure, an inflammatory disorder, an immune disorder, a cardiovascular disease, an effect of aging or an infectious disease comprising administering an effective amount of a Compound of the Invention. The invention further relates to the use of a Compound of the Invention as a preservative of a cell, blood, tissue or an organ or as an agent to modulate stem cells.
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