发明授权
- 专利标题： MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS
- 专利标题（中）： 大环肽有效对抗丙型肝炎病毒
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申请号： EP03809217.7申请日： 2003-10-20
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公开(公告)号： EP1558632B1公开(公告)日： 2009-09-23
- 发明人: LLINAS-BRUNET, Montse , BAILEY, Murray, D.
- 申请人： Boehringer Ingelheim International GmbH
- 申请人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： Binger Strasse 173 55216 Ingelheim am Rhein DE
- 代理机构： Hammann, Heinz
- 优先权： US421414P 20021025; US433820P 20021216; US442768P 20030127
- 国际公布： WO2004037855 20040506
- 主分类号： C07K5/08
- IPC分类号： C07K5/08 ; A61K38/06
摘要：
Compounds of formula (I): wherein R1 is (C1-8)alkyl, (C3-7)cycloalkyl, {(C1-6)alkyl-(C3-7)cycloalkyl} or Het, which are all optionally substituted from 1 to 3 times with halo, cyano, nitro, O-(C1-6)alkyl, amido, amino or phenyl, or R1 is C6 or C10 aryl which is optionally substituted from 1 to 3 times with halo, cyano, nitro, (C1-6)alkyl, O-(C1-6)alkyl, amido, amino or phenyl; or a pharmaceutically acceptable salt thereof, useful as an inhibitor of the HCV NS3 protease.
公开/授权文献
- EP1558632A1 MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS 公开/授权日：2005-08-03
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