发明公开
- 专利标题: 17 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 INHIBITORS FOR THE TREATMENT OF ANDROGEN DEPENDENT DISEASES
- 专利标题(中): 第17β-羟基TYPE 3用于治疗雄激素病抑制剂
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申请号: EP03790505.6申请日: 2003-12-15
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公开(公告)号: EP1572299A1公开(公告)日: 2005-09-14
- 发明人: GUZI, Timothy, J. , LIU, Yi-Tsung , DOLL, Ronald, J. , SAKSENA, Anil , GIRIJAVALLABHAN, Viyyoor, M. , PACHTER, Jonathan, A.
- 申请人: SCHERING CORPORATION
- 申请人地址: 2000 Galloping Hill Road Kenilworth, New Jersey 07033-0530 US
- 专利权人: SCHERING CORPORATION
- 当前专利权人: SCHERING CORPORATION
- 当前专利权人地址: 2000 Galloping Hill Road Kenilworth, New Jersey 07033-0530 US
- 代理机构: UEXKÜLL & STOLBERG
- 优先权: US434101P 20021217
- 国际公布: WO2004060488 20040722
- 主分类号: A61P5/28
- IPC分类号: A61P5/28 ; A61P35/00 ; A61K31/496 ; A61K31/4545 ; C07D401/14
摘要:
The present invention provides a novel class of compounds of formula (I): as inhibitors of type 3 17β-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17β-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
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