发明授权
EP1590341B1 2-AMINOPYRIDINE SUBSTITUTED HETEROCYCLES AS INHIBITORS OF CELLULAR PROLIFERATION
有权
2-氨基吡啶SUBSTITUIERTEHETEROCYCLEN AS细胞增殖的抑制剂的
- 专利标题： 2-AMINOPYRIDINE SUBSTITUTED HETEROCYCLES AS INHIBITORS OF CELLULAR PROLIFERATION
- 专利标题（中）： 2-氨基吡啶SUBSTITUIERTEHETEROCYCLEN AS细胞增殖的抑制剂的
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申请号： EP04701058.2申请日： 2004-01-09
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公开(公告)号： EP1590341B1公开(公告)日： 2009-06-17
- 发明人: FLAMME, Cathlin M., Pfizer Global R & D , McNAMARA, Dennis J., Pfizer Global R & D , REPINE, Joseph T., Pfizer Global R & D , TOOGOOD, Peter L., Pfizer Global R & D , VANDERWEL, Scott N., Pfizer Global R & D , WARMUS, Joseph S., Pfizer Global R & D
- 申请人： Warner-Lambert Company LLC
- 申请人地址： 235 East 42nd Street New York, NY 10017 US
- 专利权人： Warner-Lambert Company LLC
- 当前专利权人： Warner-Lambert Company LLC
- 当前专利权人地址： 235 East 42nd Street New York, NY 10017 US
- 代理机构： Dekker, Henrike Cornelie Christine
- 优先权： US440805P 20030117
- 国际公布： WO2004065378 20040805
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; C07D213/75
摘要：
The present invention provides substituted 2-aminopyridines of formula (I), wherein R1, A1, W, X, and Y are as defined in the specification, useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (Cdk4).
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