发明公开
EP1594854A4 THIAZOLYL-BASED COMPOUNDS USEFUL AS KINASE INHIBITORS
有权
作为激酶抑制剂的ON THIAZOLYLBASIS合适的化合物
- 专利标题： THIAZOLYL-BASED COMPOUNDS USEFUL AS KINASE INHIBITORS
- 专利标题（中）： 作为激酶抑制剂的ON THIAZOLYLBASIS合适的化合物
-
申请号： EP04709122申请日： 2004-02-06
-
公开(公告)号： EP1594854A4公开(公告)日： 2007-07-18
- 发明人: HYNES JOHN , WU HONG , LEFTHERIS KATERINA , LIU CHUNJIAN , DAS JAGABANDHU , MOQUIN ROBERT V
- 申请人： SQUIBB BRISTOL MYERS CO
- 专利权人： SQUIBB BRISTOL MYERS CO
- 当前专利权人： SQUIBB BRISTOL MYERS CO
- 优先权： US44541003 2003-02-06
- 主分类号： C07D277/34
- IPC分类号： C07D277/34 ; A61K20060101 ; A61K31/426 ; A61K31/4439 ; A61P29/00 ; C07D277/46 ; C07D277/56 ; C07D417/02 ; C07D417/12
摘要：
The present invention provides thiazolyl-based compounds of formula (I), useful for treating p38 kinase-associated conditions, wherein ring A is phenyl or pyridyl, and X, Y, B, R2, R3, Z1 m and n are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.
信息查询
