发明公开
EP1595143A1 THE DETECTION AND IDENTIFICATION OF SAXIPHILINS USING SAXITOXIN-BIOTIN CONJUGATES
审中-公开
检测和SAXIPHILINEN的识别方法石房蛤毒素生物素结合物
- 专利标题: THE DETECTION AND IDENTIFICATION OF SAXIPHILINS USING SAXITOXIN-BIOTIN CONJUGATES
- 专利标题(中): 检测和SAXIPHILINEN的识别方法石房蛤毒素生物素结合物
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申请号: EP04710306.4申请日: 2004-02-12
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公开(公告)号: EP1595143A1公开(公告)日: 2005-11-16
- 发明人: ROBILLOT, Cédric, Emile, François
- 申请人: AUSTRALIAN INSTITUTE OF MARINE SCIENCE , Cleveland Biosensors Pty Ltd
- 申请人地址: PMB No. 3 Townsville, QLD 4810 AU
- 专利权人: AUSTRALIAN INSTITUTE OF MARINE SCIENCE,Cleveland Biosensors Pty Ltd
- 当前专利权人: AUSTRALIAN INSTITUTE OF MARINE SCIENCE,Cleveland Biosensors Pty Ltd
- 当前专利权人地址: PMB No. 3 Townsville, QLD 4810 AU
- 代理机构: Pilkington, Stephanie Joan
- 优先权: AU2003901897 20030212
- 国际公布: WO2004072640 20040826
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; C07D487/14
摘要:
A method for capturing a saxiphilin to allow for detection, characterisation, isolation an/or purification of said saxiphilin or its ligand, comprising: (1) providing a PST conjugate comprising a PST moiety bound via a linker through a site other than the binding site for saxiphilin directly or indirectly to a biotin moiety; (2) exposing the PST conjugate to a sample putatively containing said saxiphilin to create a reaction mixture and to (strept)avidin; and (3) allowing binding through the PST moiety to the saxiphilin and through the biotin moiety to (strept)avidin to form a captured PST complex.
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