发明公开
EP1599477A1 SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS
有权
SULFONAMIDSUBSTITUIERTE克桑西衍生物FOR USE AS PEPCK抑制剂
- 专利标题: SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS
- 专利标题(中): SULFONAMIDSUBSTITUIERTE克桑西衍生物FOR USE AS PEPCK抑制剂
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申请号: EP04710346.0申请日: 2004-02-12
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公开(公告)号: EP1599477A1公开(公告)日: 2005-11-30
- 发明人: FOLEY, Louise, Helen , HUBY, Nicholas, John, Silvester , PIETRANICO-COLE, Sherrie, Lynn , YUN, Weiya , DUNTEN, Pete, William
- 申请人: F. HOFFMANN-LA ROCHE AG
- 申请人地址: Grenzacherstrasse 124 4070 Basel CH
- 专利权人: F. HOFFMANN-LA ROCHE AG
- 当前专利权人: F. HOFFMANN-LA ROCHE AG
- 当前专利权人地址: Grenzacherstrasse 124 4070 Basel CH
- 代理机构: Klostermeyer, Dörte
- 优先权: US448562P 20030219
- 国际公布: WO2004074288 20040902
- 主分类号: C07D473/04
- IPC分类号: C07D473/04 ; A61K31/52 ; A61P3/10
摘要:
The present invention is concerned with sulfonamide substituted xanthine derivatives of formula (I) or a pharmaceutically acceptable salts or prodrugs thereof, wherein R1, R2 and R3 are as defined in the specification. Compounds of formula (I) and pharmaceutically acceptable salts or prodrugs thereof show activity as modulators of gluconeogenesis.
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